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Promising Biotechnological Approach Significantly Reduces the Cost of Key Anticancer Drug

The Kampranis Research Team, at the University of Copenhagen—a Twin4Promis advanced partner—has made a significant step toward suggesting a way to lower the cost and environmental impact of producing paclitaxel (Taxol), a widely used chemotherapy drug for cancers such as breast, ovarian, and lung cancer. Paclitaxel is a complex naturally-derived compound from the Pacific yew…

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New in ACS Synthetic Biology: Optimization of a High-Throughput Screen for Monitoring Disease-Linked Protein Misfolding in Bacteria

Skretas Lab has been leveraging the fluorescence of Escherichia coli bacteria engineered to express fusions of misfolding-prone (MisP) human proteins with green fluorescent protein (GFP) as a high-throughput screening readout for identifying chemical compounds that rescue disease-associated protein misfolding and aggregation. In a newly published study in ACS Synthetic Biology, the team defined conditions that…

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Highlights from Dr. Georgios Skretas’ Talk at the 3rd Panhellenic Student Conference of Bioscientists

From March 28 to 30, 2025, the city of Alexandroupoli, Greece hosted the inspiring 3rd Panhellenic Student Conference of Bioscientists, bringing together students, researchers, and innovators from across Greece. One of the presentations on the opening day, March 28, was given by Dr. Georgios Skretas entitled “Beneficial microbes as platforms for the discovery of novel,…

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Efficient Protein Discovery Made Simple with ProteoSeeker

Twin4Promis presents ProteoSeeker, a breakthrough command-line tool that simplifies and accelerates protein discovery through metagenomic analysis. Developed by the Skretas Lab, this open-access resource is designed to empower researchers—regardless of computational expertise—to tap into the vast potential of microbial diversity. ProteoSeeker streamlines the process of identifying and annotating proteins in complex metagenomic datasets, operating in…

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Driving Innovation at NextGen Biomed 2025: Dr. Skretas to Speak on Microbial Solutions for Protein Misfolding

Dr. Georgios Skretas, Coordinator of the Twin4Promis project, will be giving an invited lecture at the NextGen Biomed 2025 conference, held in London, UK, on March 13-15, 2025. His talk is scheduled for 16:55 on March 13, and is entitled:“Engineering Microbes for the Discovery of Cyclic Oligopeptide Rescuers of Pathogenic Protein Misfolding & Aggregation” NextGen…

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Empowering Researchers through Short-Term Scientific Missions

In her recent article, Vassiliki Michopoulou, our Science Communication Manager, highlights the value of Short Term Scientific Missions (STSMs) for the professional growth of young researchers. The article features insights from four young researchers, including Effie Karyda, who share their life-changing experiences of participating in these international laboratory missions. Effie Karyda, a junior PhD student…

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CO₂ Capture Research Featured on “ECO News by DEI S.A.”

Dr. Dimitra Zarafeta, a young researcher and Twin4Promis project manager, was recently featured in an interview on the TV show “ECO News by DEI S.A.” on ΣΚΑΪ TV. Dr. Zarafeta discussed the recently published and patent-pending research on a new enzyme with the potential to revolutionize CO₂ capture, marking a significant advancement in the fight…

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Dr. Georgios Skretas to Open the 1st Student Conference in Biotechnology as Keynote Speaker

We are delighted to announce that our Twin4Promis coordinator, Dr. Georgios Skretas, will be participating as a keynote speaker at the 1st Student Conference in Biotechnology. The conference will be held from November 1st to November 3rd, 2024, at the Agricultural University of Athens. Dr. Skretas’s presentation “Microbial Cell Factories as a Drug Discovery Platform”…

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Dr. Skretas at GENEDIS 2024 as Keynote Speaker

We are excited to announce that Dr. Georgios Skretas, the Coordinator of the Twin4promis project, will be participating in the upcoming 6th Genomics, Neuroscience, Therapeutics, and Data Innovation Summit (GeNeDis 2024) as a keynote speaker. This event will take place from Thursday, October 17 to Sunday, October 20, 2024, in Athens, Greece. GeNeDis is a…

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