The project partners wish to exploit their complementary technologies and skills in biology, chemistry and engineering to widen their collaboration and synergize to expand their research to studying the misfolding of membrane proteins. By doing so and in the framework of an exploratory R&I project carried out with open science practices, they aim to identify new compounds with the ability to rescue the misfolding of disease-linked integral membrane proteins, select candidate molecules with potentially therapeutic effects against serious and currently incurable diseases, and expedite their further development and commercial exploitation.