May 2025

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Promising Biotechnological Approach Significantly Reduces the Cost of Key Anticancer Drug

The Kampranis Research Team, at the University of Copenhagen—a Twin4Promis advanced partner—has made a significant step toward suggesting a way to lower the cost and environmental impact of producing paclitaxel (Taxol), a widely used chemotherapy drug for cancers such as breast, ovarian, and lung cancer. Paclitaxel is a complex naturally-derived compound from the Pacific yew…

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New in ACS Synthetic Biology: Optimization of a High-Throughput Screen for Monitoring Disease-Linked Protein Misfolding in Bacteria

Skretas Lab has been leveraging the fluorescence of Escherichia coli bacteria engineered to express fusions of misfolding-prone (MisP) human proteins with green fluorescent protein (GFP) as a high-throughput screening readout for identifying chemical compounds that rescue disease-associated protein misfolding and aggregation. In a newly published study in ACS Synthetic Biology, the team defined conditions that…

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