From September 9 to 11, 2024, the VIB Switch Laboratory in Leuven, Belgium, the epicenter of biophysics innovation, served as a host for the Twin4Promis Biophysics Workshop. This event was designed to meet the needs of students and postdoctoral researchers, providing a rich, hands-on learning experience in the cutting-edge techniques of the VIB Switch Laboratory’s biophysics platform.

The workshop’s core focus was on pivotal methodologies for analyzing protein aggregation and protein-protein interactions—both critical areas in understanding the molecular underpinnings of neurodegenerative diseases and characterizing potential inhibitors of aggregation for different targets. Through a blend of theoretical insights and practical exercises, attendees gained an invaluable understanding of how these techniques can be applied to their own research.

Key Highlights of the Workshop:

• Expert-Led Sessions: The workshop featured sessions led by experts in biophysics, who shared their extensive knowledge on advanced techniques and their applications in current research.
• Hands-On Learning: Participants engaged in practical exercises that allowed them to apply biophysics techniques to test aggregation-inhibitor candidates for different targets. This hands-on approach was designed to enhance their technical skills and provide them with a deeper understanding of the methodologies.
• Networking Opportunities: The event fostered a collaborative environment, encouraging attendees to connect with peers and experts in the field. This networking aspect was instrumental in promoting future collaborations and research partnerships.
• Focus on Neurodegenerative Diseases: Given the significance of biophysics in studying neurodegenerative diseases, the workshop placed a strong emphasis on techniques relevant to this area. This focus provided participants with specialized knowledge that could be directly applied to their research on conditions such as Alzheimer’s and Parkinson’s diseases.

The Twin4Promis Biophysics Workshop not only greatly expanded participants’ knowledge in advanced biophysical techniques but also inspired them to push the boundaries of their research. By combining theoretical learning with practical experience, the workshop successfully equipped the next generation of scientists with the tools and insights needed to advance their research and will ultimately help them to contribute significantly not only to the field of neurodegeneration, but also other fields relevant to protein aggregation.