Michele Vendruscolo is Professor of Biophysics, Director of the Chemistry of Health Laboratory and Co-Director of the Centre for Misfolding Diseases at the Department of Chemistry of the University of Cambridge where he moved over 20 years ago. His work is aimed at establishing the fundamental principles of protein homeostasis and protein aggregation, and at exploiting these principles to develop methods for drug discovery in neurodegenerative diseases. He has published over 500 scientific papers and 20 patents, and given over 500 invited lectures at international meetings. He is co-founder of Wren Therapeutics, a drug discovery company that targets protein misfolding diseases.